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The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension
Authors:Hennigs  Jan K  Lüneburg  Nicole  Stage  Annett  Schmitz  Melanie  Körbelin  Jakob  Harbaum  Lars  Matuszcak  Christiane  Mienert  Julia  Bokemeyer  Carsten  Böger  Rainer H  Kiefmann  Rainer  Klose  Hans
Institution:1.Department of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
;2.Center for Pulmonary Arterial Hypertension Hamburg, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
;3.II. Department of Internal Medicine, Center of Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
;4.Institute of Clinical Pharmacology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
;5.Department of Anesthesiology, Center of Anesthesiology and Critical Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
;
Abstract:Purinergic Signalling - Dysfunction of the pulmonary endothelium is associated with most lung diseases. Extracellular nucleotides modulate a plethora of endothelial functions in the lung such as...
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