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Imidazo[2,1-b]thiazoles: Multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases
Authors:Steve D. Fidanze  Scott A. Erickson  Gary T. Wang  Robert Mantei  Richard F. Clark  Bryan K. Sorensen  Nwe Y. Bamaung  Peter Kovar  Eric F. Johnson  Kerren K. Swinger  Kent D. Stewart  Qian Zhang  Lora A. Tucker  William N. Pappano  Julie L. Wilsbacher  Jieyi Wang  George S. Sheppard  Randy L. Bell  Steven K. Davidsen  Robert D. Hubbard
Affiliation:Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA
Abstract:The design and enzyme activities of a novel class of imidazo[2,1-b]thiazoles is presented.
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