Autocrine stimulation of P2Y1 receptors is part of the purinergic signaling mechanism that regulates T cell activation |
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Authors: | Woehrle Tobias Ledderose Carola Rink Jessica Slubowski Christian Junger Wolfgang G. |
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Affiliation: | 1.Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA ;2.Department of Anesthesiology, Ludwig Maximilian University, Munich, Germany ;3.Ludwig Boltzmann Institute for Traumatology, Vienna, Austria ; |
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Abstract: | Purinergic Signalling - Previous studies have shown that T cell receptor (TCR) and CD28 coreceptor stimulation involves rapid ATP release, autocrine purinergic feedback via P2X receptors, and... |
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