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Autocrine stimulation of P2Y1 receptors is part of the purinergic signaling mechanism that regulates T cell activation
Authors:Woehrle  Tobias  Ledderose  Carola  Rink  Jessica  Slubowski  Christian  Junger  Wolfgang G.
Affiliation:1.Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
;2.Department of Anesthesiology, Ludwig Maximilian University, Munich, Germany
;3.Ludwig Boltzmann Institute for Traumatology, Vienna, Austria
;
Abstract:Purinergic Signalling - Previous studies have shown that T cell receptor (TCR) and CD28 coreceptor stimulation involves rapid ATP release, autocrine purinergic feedback via P2X receptors, and...
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