| 肿瘤的分子治疗新进展 |
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| 引用本文： | 李招发,惠二京,连文昌. 肿瘤的分子治疗新进展[J]. 生物技术通报, 2011, 0(4) |
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| 作者姓名： | 李招发 惠二京 连文昌 |
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| 作者单位： | 1. 华侨大学分子药物学研究所,泉州,362021;华侨大学分子药物教育部工程研究中心,泉州,362021
2. 华侨大学分子药物学研究所,泉州,362021 |
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| 基金项目： | 福建省自然科学基金项目，福建省重点项目 |
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| 摘 要： | 肿瘤的发生、发展是一个多步骤、多基因参与的、复杂的系统性过程.分子治疗作为21世纪最有希望根治人类肿瘤的技术,其治疗技术的关键在于靶分子的选择,寻找合适的靶分子一直是分子治疗肿瘤的重要方向.针对近年来肿瘤治疗研究中发现的端粒酶靶标、抗血管生成基因靶标、apoptin、survivin、stathmin、autophagy、PUMA、转铁蛋白受体靶标和相应的治疗策略作一综述.
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| 关 键 词： | 肿瘤 分子治疗 靶标 |
Research Development of Cancer Molecular Therapy |
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| Li Zhaofa,Hui Erjing,Lian Wenchang. Research Development of Cancer Molecular Therapy[J]. Biotechnology Bulletin, 2011, 0(4) |
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| Authors: | Li Zhaofa Hui Erjing Lian Wenchang |
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| Affiliation: | Li Zhaofa1,2 Hui Erjing1 Lian Wenchang1(1Institute of Molecular Medicine,Huaqiao University,Quanzhou 362021,2Molecular Medicine Engineering Research Center of the Ministry of Education,Quanzhou 362021) |
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| Abstract: | The tumor occurrence,development as a systemic and complex process involves multi-step and multi-gene interaction.Molecular therapy as the most promising of human radical treatment technology in the 21st century,the key is how to find a suitable target molecular that is an important direction for cancer molecular therapy.This literature discussed some molecular targets,such as telomerase,anti-angiogenesis,apoptin,survivin,stathmin,autophagy,PUMA,transferrin receptor and the corresponding new molecular thera... |
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| Keywords: | Tumor Molecular therapy Target |
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