Microbial pathogenesis: lipid rafts as pathogen portals |
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| Authors: | Rosenberger C M Brumell J H Finlay B B |
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| Institution: | Biotechnology Laboratory and Department of Microbiology and Immunology, University of British Columbia, British Columbia V6T 1Z3, Vancouver, Canada. |
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| Abstract: | The route of initial entry influences how host cells respond to intracellular pathogens. Recent studies have demonstrated that a wide variety of pathogens target lipid microdomains in host cell membranes, known as lipid rafts, to enter host cells as an infectious strategy. |
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