Developmental control of the expression of two ten-sugar branched chain fucolipids in rat small intestine |
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Authors: | Danièle Bouhours Jean-François Bouhours |
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Affiliation: | (1) Laboratoire de Biologie et Technologie des Membranes du Cente National de la Recherche Scientifique, Université Claude-Bernard, 43 Boulevard du 11 Novembre 1918, 69622 Villeurbanne Cedex, France |
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Abstract: | Two branched decaglycosylceramides, apparently identical to those identified in the small intestine of adult rats [Breimer ME, Falk K-E, Hansson GC, Karlsson K-A (1982) J Biol Chem 257:50–59], were absent during the three weeks following birth. They appeared abruptly at around 21 days. After their appearance, their tissue concentration and their base composition did not change during development. Their fatty acids were non-hydroxylated and the percentage of C22–C24 fatty acids, which was low at 24 days, increased and reached 48.6% by 27 days.Nomenclature Gal1-4Gal1-4GlcCer Globotriaosylceramide (GbOse3Cer) - Il3NeuAc-LacCer MM3-ganglioside - GalNAc1-3Gal1-4Gal1-4GlcCer globoside (globotetraosylceramide, GbOse4Cer) |
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Keywords: | branched-chain glycosphingolipds fucolipids development rat small intestine |
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