| 微生物酶催化腈水解反应的研究进展 |
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| 引用本文： | 娄文勇,宗敏华,刘森林. 微生物酶催化腈水解反应的研究进展[J]. 微生物学通报, 2001, 28(6): 76-81 |
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| 作者姓名： | 娄文勇 宗敏华 刘森林 |
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| 作者单位： | 华南理工大学生物工程系,广州,510640 |
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| 基金项目： | 国家自然科学基金资助项目 (No .2 0 0 76 0 1 9)~~ |
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| 摘 要： | 腈的酶法水解不仅反应条件温各，而且高效性、高选择性，在光学活性羧酸及其衍生物的合成中具有巨大的应用潜力。综述了催化腈水解的酶类、反应类型、反应特性、影响反应的因素及其在工业上的应用前景。
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| 关 键 词： | 腈水解 腈水解酶 腈水合酶 微生物酶 |
| 文章编号： | 0253-2654(2001)06-0076-06 |
| 修稿时间： | 2000-10-08 |
RESEARCH PROGRESS ON ENZYMATIC HYDROLYSIS OF NITRILE |
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| LOU Wen-Yong ZONG Min-Hua LIU Sen-Lin. RESEARCH PROGRESS ON ENZYMATIC HYDROLYSIS OF NITRILE[J]. Microbiology China, 2001, 28(6): 76-81 |
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| Authors: | LOU Wen-Yong ZONG Min-Hua LIU Sen-Lin |
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| Abstract: | Enzymatic hydrolysis of nitrile was performed under mild conditions and afford high efficiency and selectivity,thus being highly potential for the synthesis of optically active carboxylic acids and their derivatives.The type of nitrile-hydrolyzing enzymes and hydrolysis reactions,reaction characteristics,factors influencing the hydrolysis and the prospect for its application to industrial production were reviewed in this paper. |
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| Keywords: | Nitrile hydrolysis Nitrilase Nitrile hydratase |
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