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Structural analysis of the Alu-containing DNA fragment with disperse distribution in human chromosomes
Authors:I Z Za?tsev  V M Gindilis  Iu A Shapiro  Iu B Iurov  A G Iakovlev
Abstract:Nucleotide sequencing of two terminal subfragments of a cloned human DNA fragment has been done. The fragment cloned hybridized dispersively along all chromosomes except for Y chromosome and C heterochromatic chromosome regions. Both subfragments sequenced contain Alu repeats, whose structures differ partially from those of accurately determined sequences of human Alu repeats. The results obtained are discussed in respect of possible usage of Alu repeats containing sequences for construction of special polymorphic molecular markers of human chromosomes.
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