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The prognostic value of MR-proadrenomedullin in patients with acute coronary syndrome complicated by cardiogenic shock |
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| Authors: | Karolina Supeł Michał Kacprzak Marzenna Zielińska |
| Institution: | Department of Interventional Cardiology and Electrocardiology, Intensive Cardiac Therapy Clinic, Medical University of Lodz, Poland |
| Abstract: | Context: Cardiogenic shock (CS) still remains one of the main causes of death in acute myocardial infarction (AMI). Objective: The aim of this study was to evaluate the prognostic value of midregional (MR)-proadrenomedullin in AMI complicated by CS. Methods: Forty-seven consecutive patients were included in our prospective observational study. All patients underwent coronarography and successful percutaneous coronary intervention (PCI). Plasma levels of MR-proADM were measured by a immunofluorescence method. The primary endpoint of the study, defined as cardiovascular death, occurred in 17 patients (36%). Results and conclusion: Elevated plasma level of MR-proADM, determined 24?h after diagnosis of CS could be a predictor of in-hospital mortality in patients with AMI complicated by CS. |
| Keywords: | Cardiogenic shock myocardial infarction MR-proadrenomedullin |