Microwave assisted facile synthesis of amino acid benzyl ester p-toluenesulfonate and hydrochloride salts |
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Authors: | Ganga-Ramu Vasanthakumar Basanagoud S. Patil Vommina Venkata Suresh Babu |
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Affiliation: | (1) Department of Studies in Chemistry, Central College Campus, Bangalore University, Dr. B. R. Ambedkar Veedhi, Bangalore, 560 001, India |
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Abstract: | A simple method for the synthesis of several amino acidbenzyl ester p-toluenesulfonate salts from thecorresponding amino acid and benzyl alcohol in presence of p-toluenesulfonic acid accelerated with microwave irradiation isdescribed. Under similar condition, the amino acid benzyl esterhydrochloride salts have also been obtained by using thionylchloride instead of p-toluenesulfonic acid in good yieldand purity. |
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Keywords: | benzyl ester esterification hydrochloride salt microwave irradiation p-toluenesulfonate salt |
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