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Microwave assisted facile synthesis of amino acid benzyl ester p-toluenesulfonate and hydrochloride salts
Authors:Ganga-Ramu Vasanthakumar   Basanagoud S. Patil  Vommina Venkata Suresh Babu
Affiliation:(1) Department of Studies in Chemistry, Central College Campus, Bangalore University, Dr. B. R. Ambedkar Veedhi, Bangalore, 560 001, India
Abstract:A simple method for the synthesis of several amino acidbenzyl ester p-toluenesulfonate salts from thecorresponding amino acid and benzyl alcohol in presence of p-toluenesulfonic acid accelerated with microwave irradiation isdescribed. Under similar condition, the amino acid benzyl esterhydrochloride salts have also been obtained by using thionylchloride instead of p-toluenesulfonic acid in good yieldand purity.
Keywords:benzyl ester  esterification  hydrochloride salt  microwave irradiation  p-toluenesulfonate salt
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