Local expression of interferon-alpha and interferon receptors in cervical intraepithelial neoplasia |
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| Authors: | Nelson R Tirone Bethanea C Peghini Ana Cristina M Barcelos Eddie F C Murta Marcia A Michelin |
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| Institution: | 1.Research Institute of Oncology (IPON),Federal University of Triangulo Mineiro (UFTM),Minas Gerais,Brazil;2.Discipline of Gynecology and Obstetrics, Research Institute of Oncology (IPON),Federal University of Triangulo Mineiro (UFTM),Minas Gerais,Brazil |
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| Abstract: | Purpose The present study evaluated mRNA expression of interferon-alpha (IFN-α), IFN-α receptor subunits (IFNAR-1 and IFNAR-2) and
an IFN-stimulated gene encoding the enzyme 2′,5′-oligoadenylate synthetase (2′5′OAS) in biopsies on patients with varying
grades of cervical intraepithelial neoplasia (CIN I, II and III). |
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