Enhancement of cardiomyocyte differentiation from human embryonic stem cells |
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| Authors: | YanXia Wang GuiAn Chen TianRan Song GenHong Mao HaiYan Bai |
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| Institution: | (1) The Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University, Petit Institute for Bioengineering and Bioscience, Atlanta, GA, USA; |
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| Abstract: | Several approaches have been used to encourage the differentiation of cardiomyocytes from human embryonic stem cells.However,the differentiation efficiency is low,and appropriate culture protocols are needed to produce adequate numbers of cardiomyocytes for therapeutic cell transplantation.This study investigated the effects of serum on cardiomyocyte differentiation in suspension culture medium during embryoid body(EB) formation by human embryonic stem cells.The addition of ascorbic acid,dimethylsulfoxide a... |
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| Keywords: | human embryonic stem cells cardiomyocyte differentiation serum ascorbic acid 5-aza-dC |
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