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Fungal 17β-hydroxysteroid dehydrogenase
Authors:Tea Lani&#;nik  Marija &#;akelj-Mavri&#;  Igor Beli&#;
Institution:Institute of Biochemistry, Medical Faculty, University of Ljubljana, Slovenia.
Abstract:Two representatives of each of different fungal taxonomic classes were tested for constitutive 17 beta-hydroxysteroid dehydrogenase (HSDH) activity and the results were positive in all cases. The enzyme was found to be regioselective for C17 of the steroid ring and 20 beta-HSDH activity was only detected in Trichoderma viride. In most cases the oxidative pathway is favoured over the reductive pathway. The possible role of this enzyme in fungi is discussed.
Keywords:Fungi  17β-Hydroxysteroid dehydrogenase  Steroid oxidoreduction  Trichoderma viride
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