Fungal 17β-hydroxysteroid dehydrogenase |
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Authors: | Tea Laninik Marija akelj-Mavri Igor Beli |
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Institution: | Institute of Biochemistry, Medical Faculty, University of Ljubljana, Slovenia. |
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Abstract: | Two representatives of each of different fungal taxonomic classes were tested for constitutive 17 beta-hydroxysteroid dehydrogenase (HSDH) activity and the results were positive in all cases. The enzyme was found to be regioselective for C17 of the steroid ring and 20 beta-HSDH activity was only detected in Trichoderma viride. In most cases the oxidative pathway is favoured over the reductive pathway. The possible role of this enzyme in fungi is discussed. |
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Keywords: | Fungi 17β-Hydroxysteroid dehydrogenase Steroid oxidoreduction Trichoderma viride |
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