Tissue variability of the phosphotransferases adenylate kinase (EC: 2.7.4.3.) and pyruvate kinase (EC: 2.7.1.40.)

Summary Studies of the tissue variability of human AK and PK are reported. Homozygous probands of phenotype AK 1, show five electrophoretic positions with AK activity in different tissues and six positions with PK activity. In one of the 20 probands studied the brain, not however any other tissue, revealed a different zymogram. It can be followed therefore that different isozymes can be present in different tissues.Head: Prof. Dr. Dr. H. BaitschSupported by the Deutsche Forschungsgemeinschaft.