| 白藜芦醇合成酶基因在基因工程中的应用及功能研究进展 |
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| 引用本文： | 郑世刚,李臻,赵善仓,王庆国,刘炜.白藜芦醇合成酶基因在基因工程中的应用及功能研究进展[J].生物工程学报,2014,30(3):341-354. |
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| 作者姓名： | 郑世刚 李臻 赵善仓 王庆国 刘炜 |
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| 作者单位： | 青岛农业大学生命科学学院，山东 青岛 266000；山东省农业科学院生物技术研究中心和山东省作物遗传改良与生态生理重点实验室，山东 济南 250100;山东省农业科学院生物技术研究中心和山东省作物遗传改良与生态生理重点实验室，山东 济南 250100;山东省农业科学院农业质量标准与检测技术研究所，山东 济南 250100;山东省农业科学院生物技术研究中心和山东省作物遗传改良与生态生理重点实验室，山东 济南 250100;青岛农业大学生命科学学院，山东 青岛 266000；山东省农业科学院生物技术研究中心和山东省作物遗传改良与生态生理重点实验室，山东 济南 250100 |
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| 基金项目： | 国家转基因植物新品种培育重大专项 (No. 2009ZX08001-010B)，山东省农业良种工程 (2012-2014) 资助。 |
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| 摘 要： | 白藜芦醇合成酶(Resveratrol synthase,RS)是白藜芦醇(Resveratrol,Res)合成途径中的关键酶。以往研究报道,RS基因已在多种植物和微生物中进行了转化和表达,并在植物的代谢及调控等方面发挥生物学作用。文中主要围绕RS基因对植物的转化,及异源表达后植物体内代谢产物的变化,转RS基因对植物抗病原菌活性、抗自由基活性和生长发育的影响,以及利用RS基因在微生物中生产Res的相关进展进行了综述。并对RS基因在生物工程方面的应用前景进行展望。
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| 关 键 词： | 白藜芦醇合成酶基因 白藜芦醇 代谢 生物功能 应用前景 |
| 收稿时间： | 2013/5/21 0:00:00 |
Advances of resveratrol synthase gene in the application of genetic engineering and biofunctional investigation |
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| Shigang Zheng,Zhen Li,Shancang Zhao,Qingguo Wang and Wei Liu.Advances of resveratrol synthase gene in the application of genetic engineering and biofunctional investigation[J].Chinese Journal of Biotechnology,2014,30(3):341-354. |
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| Authors: | Shigang Zheng Zhen Li Shancang Zhao Qingguo Wang and Wei Liu |
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| Institution: | College of Life Science, Qingdao Agricultural University, Qingdao 266000, Shandong, China; Bio-Tech Research Center, Shandong Academy of Agricultural Sciences; Key Laboratory of Genetic Improvement, Ecology and Physiology of Crops, Shandong Province, Jinan 250100, Shandong, China;Bio-Tech Research Center, Shandong Academy of Agricultural Sciences; Key Laboratory of Genetic Improvement, Ecology and Physiology of Crops, Shandong Province, Jinan 250100, Shandong, China;Agricultural Quality Standards and Testing Technology Institute of Shandong Academy of Agricultural Sciences, Jinan 250100, Shandong, China;Bio-Tech Research Center, Shandong Academy of Agricultural Sciences; Key Laboratory of Genetic Improvement, Ecology and Physiology of Crops, Shandong Province, Jinan 250100, Shandong, China;College of Life Science, Qingdao Agricultural University, Qingdao 266000, Shandong, China; Bio-Tech Research Center, Shandong Academy of Agricultural Sciences; Key Laboratory of Genetic Improvement, Ecology and Physiology of Crops, Shandong Province, Jinan 250100, Shandong, China |
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| Abstract: | Resveratrol synthase (RS) plays a key role in resveratrol (Res) biosynthesis. RS gene has been formerly reported to be transformed into many plant species and microorganisms, and to play certain roles in metabolic and regulation processes. In this paper, the transformations of RS gene in plants, and the related changes of biological properties, such as metabolites, anti-pathogen activities, anti-radical properties, and developmental characters in transgenic plants, as well as the production of resveratrol in microbes by utilizing RS gene were summarized. Moreover, the application prospects of RS gene in bioengineering were also addressed. |
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| Keywords: | resveratrol synthase gene resveratrol metabolism biological properties application prospects |
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