Iron-regulated membrane proteins and bacterial virulence |
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| Authors: | E. Griffiths |
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| Affiliation: | (1) National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, EN6 3QG Hertfordshire, England |
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| Abstract: | The amount of iron that might be readily available to bacteria in body fluids is extremely small. This iron restricted environment induces phenotypic changes in the metabolism and in the composition of the membrane proteins of bacteria growingin vivo. These changes are now providing a fresh insight into the capabilities of bacteria to multiply in host tissues and are suggesting new possibilities for targetting therapeutic and prophylactic measures. |
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| Keywords: | Bacterial virulence iron-regulated membrane proteins |
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