| 核酸疫苗的研究及应用进展 |
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| 引用本文： | 李月涛,霍金龙,信吉阁,曾养志. 核酸疫苗的研究及应用进展[J]. 生物技术通报, 2006, 0(4): 1-5,15 |
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| 作者姓名： | 李月涛 霍金龙 信吉阁 曾养志 |
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| 作者单位： | 云南农业大学动物科技学院,昆明,650201 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 核酸疫苗(DNA疫苗)是20世纪90年代发展起来的一种新型疫苗。核酸疫苗不仅可引起体液免疫反应,而且能诱导高水平的细胞免疫应答,尤其是细胞毒T淋巴细胞(CTL)反应,被认为在病毒、细菌、寄生虫等病原体感染的防治中具有更大的优势。核酸疫苗既可作为病毒、细菌或寄生虫的预防疫苗,也可作为非感染性疾病如肿瘤病的治疗用疫苗。
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| 关 键 词： | 核酸疫苗 病毒 细菌 寄生虫 |
| 收稿时间： | 2006-03-13 |
| 修稿时间： | 2006-03-13 |
Progress on Application and Research of Nucleic Acid Vaccine |
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| Li Yuetao,Huo Jinlong,Xin Jige,Zeng Yangzhi. Progress on Application and Research of Nucleic Acid Vaccine[J]. Biotechnology Bulletin, 2006, 0(4): 1-5,15 |
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| Authors: | Li Yuetao Huo Jinlong Xin Jige Zeng Yangzhi |
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| Affiliation: | College of Animal Science and Technology ,Yunnan Agricultural University, Kunming 650201 |
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| Abstract: | Nucleic acid vaccine(DNA vaccine) has been a new vaccine since 1990s.The nucleic acid vaccine not only causes the immune response of body fluid but also leads the highlevel cell immune to reply,cytotoxic T lym-hocyte react especially.It has heavy advantage in the preventionand cure of the infection with virus,bacterium,parasite,etc.The nucleic acid vaccine is as a new biotechnology of developing in recent years,has already become one of the focuses of the vaccine research field,and get fast development.The nucleic acid vaccine can be regarded as the prevention vaccine of the virus,bacterium or parasite and as treatment vaccine of infectious diseaseand non-infectious disease. |
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| Keywords: | Nucleic acid vaccine Virus Bacterium Parasite |
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