The sheep pars tuberalis: an immunohistochemical study. Demonstration of the presence of glycoprotein and lipotropin hormones |
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Authors: | Y Tillet J Pelletier G Tramu M-M de Reviers |
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Institution: | (1) Laboratoire de Neuroendocrinologie Sexuelle, INRA, F-37380 Nouzilly, France;(2) Laboratoire de Neurocytochimie Fonctionnelle, Université de Bordeaux I, Avenue des Facultés, F-33405 Talence Cedex, France |
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Abstract: | Summary Using indirect immunofluorescence with fourteen different antisera raised against pituitary hormones and peptides, we characterized immunochemically the cells of the sheep pars tuberalis. The presence of LH-and FSH-containing cells, shown in previous studies, was also observed in the present investigation. In addition, we found TSH-containing cells, never observed in sheep, and LPH-containing cells. The latter hormone has never been found in any studied species. It appeared that a small amount of perikarya (less than 20%) were immunolabelled and, that the sheep pars tuberalis contained a majority of immunonegative cells as in the guinea-pig, rabbit and rhesus monkey. This study may contribute to a better knowledge of the function of the sheep pars tuberalis.List of abbreviations ACTH
adrenocorticotropin hormone
- BSA
bovine serum albumin
- CGRP
calcitonin gene-related peptide
- FSH
follicle stimulating hormone
- GH
growth hormone
- HSA
human serum albumin
- LH
luteinizing hormone
- LH-RH
luteinizing hormone-releasing hormone
- LPH
lipotropin hormone
- Met-enk
methionine enkephalin
- NPY
neuropeptide Y
- POMC
proopiomelanocortin
- PRL
prolactin
- TSH
thyreotrope stimulating hormone |
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