A novel cyclin provides a link between dopamine and RNA processing. |
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| Authors: | A C Nairn P Greengard |
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| Affiliation: | Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, NY 10021, USA. |
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| Abstract: | Regulation of gene expression by dopamine may play an important role in learning, reward, and addiction. Hyman and colleagues now report the characterization of ania-6, a novel cyclin that associates with RNA polymerase II and is induced by dopamine or cocaine in the neostriatum. Ania-6 may thus provide a link between dopamine and gene expression at the level of mRNA processing. |
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