Are we degenerate tetraploids? More genomes,new facts |
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Authors: | Amir Ali Abbasi |
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Institution: | (1) National Center for Bioinformatics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan;(2) Institute of Human Genetics, Philipps-University, Bahnhofstrasse 7, D35037 Marburg, Germany |
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Abstract: | Background Within the bilaterians, the appearance and evolution of vertebrates is accompanied by enormous changes in anatomical, morphological
and developmental features. This evolution of increased complexity has been associated with two genome duplications (2R hypothesis)
at the origin of vertebrates. However, in spite of extensive debate the validity of the 2R hypothesis remains controversial.
The paucity of sequence data in early years of genomic era was an intrinsic obstacle in tracking the genome evolutionary history
of chordates. |
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