|
|||||
|
|
Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands |
|
| Authors: | Paillet-Loilier Magalie Fabis Frédéric Lepailleur Alban Bureau Ronan Butt-Gueulle Sabrina Dauphin François Delarue Catherine Vaudry Hubert Rault Sylvain |
| Affiliation: | Centre d'Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, UFR des Sciences Pharmaceutiques, 5, rue Vaubénard 14032 Caen Cedex, France. |
| Abstract: | Virtual screening studies have identified a series of phenylpyrroles as novel 5-HT7 receptor ligands. The synthesis and the affinity for the 5-HT7 receptor of these phenylpyrroles are described. Some of these compounds exhibited high affinity for the 5-HT7 receptors. |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |