Proteinase activity in macrophage cultures. Effects of heparin and antithrombin |
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| Authors: | Rolf Seljelid, Gudrun B ckstr m,Ulf Lindahl |
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| Affiliation: | Rolf Seljelid, Gudrun Bäckström,Ulf Lindahl |
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| Abstract: | Mouse macrophages in vitro secrete an esterase capable of hydrolysing the chromogenic peptide substrate S-2222. The enzyme activity is inhibited by antithrombin and heparin. Also, the cells produce other hydrolytic activity, mainly associated with the cells capable of decomposing S-2160 and resistant to antithrombin and heparin. |
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