Effects of the presence of ColE1 plasmid DNA in Escherichia coli on the host cell metabolism |
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| Authors: | Zhijun Wang Li Xiang Junjie Shao Alicja Węgrzyn Grzegorz Węgrzyn |
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| Affiliation: | (1) Key Laboratory of Medical Molecular Virology, Shanghai Medical College, Fudan University, 200032 Shanghai, People's Republic of China;(2) Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, 14853, NY, USA;(3) Laboratory of Molecular Biology (affiliated with the University of Gdańsk), Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Kładki 24, 80-822 Gdańsk, Poland;(4) Department of Molecular Biology, University of Gdańsk, Kładki 24, 80-822 Gdańsk, Poland;(5) Department of Genetics and Marine Biotechnology, Institute of Oceanology, Polish Academy of Sciences, Św. Wojciecha 5, 81-347 Gdynia, Poland |
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| Abstract: | Background Although understanding of physiological interactions between plasmid DNA and its host is important for vector design and host optimization in many biotechnological applications, to our knowledge, global studies on plasmid-host interactions have not been performed to date even for well-characterized plasmids. |
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