Advances in immunoproteomics for serological characterization of microbial antigens |
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| Authors: | Falisse-Poirrier Nandini Ruelle Virginie ElMoualij Benaissa Zorzi Danièle Pierard Olivier Heinen Ernst De Pauw Edwin Zorzi Willy |
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| Institution: | Center of Research on Prion Proteins, Institute of Pharmacy-CHU, B36, Avenue de l'H?pital 1, B-4000 University of Liège, Belgium. |
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| Abstract: | We propose a multi-dimensional strategy, associating immunodetection to a protein fractionating two-dimensional liquid chromatography tool, for serological characterization of microbial antigens. The originality of such immunoproteomic approaches resides in their application in large-scale studies for rapid serotyping of micro-organisms, evaluation of immunomes and could be proposed in the development and monitoring of vaccines. |
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