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Magnesium profile in autism
Authors:Mirella Strambi  Mariangela Longini  Joseph Hayek  Silvia Berni  Francesca Macucci  Elisa Scalacci  Piero Vezzosi
Affiliation:(1) Department of Paediatrics, Obstetrics and Reproductive Medicine, Section of Neonatology and Preventive Paediatrics, Azienda Universitaria Ospedaliera Senese, Policlinico Le Scotte, Siena, Italy;(2) Neuropsychiatry Unit, Azienda Universitaria Ospedaliera Senese, Policlinico Le Scotte, Siena, Italy
Abstract:The aim of the present study was to determine and compare plasma and erythrocyte concentrations of magnesium in 12 autistic children (10 boys, 2 girls), 17 children with other autistic spectrum disorders (14 boys, 3 girls), 5 girls with classic Rett syndrome, and 14 normal children (7 boys, 7 girls) of the same age. No differences in intracellular Mg were found between controls and pathological subjects; however, autistic children and children with other autistic spectrum disorders had significantly lower plasma concentrations of Mg than normal subjects (p=0.013 and p=0.02, respectively). Although our study population was small, we conclude that children with autistic spectrum disorders require special dietary management. If these cases are diagnosed at an early stage, they can be helped through diet.
Keywords:Autistic spectrum disorders  autism  erythrocyte  magnesium  plasma  Rett syndrome
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