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Toxic tetranortriterpenes of the fruit of Melia azedarach
Authors:Peter B. Oelrichs  Michael W. Hill  Peter J. Vallely  John K. MacLeod  Tadeusz F. Molinski
Affiliation:Research School of Chemistry, Australian National University, P. O. Box 4, Canberra, A.C.T. 2600, Australia
Abstract:Four new tetranortriterpenes, meliatoxins A1, A2, B1 and B2 have been isolated and identified as toxic constituents of the fruit of Melia azedarach L. var. australasica. Toxicity and pathological results confirm that the meliatoxins are responsible for most but not all of the symptoms resulting from the ingestion of whole fruit.
Keywords:Meliaceae  white cedar tree  tetranortriterpenes  toxicity  pathology
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