Tetraoxygenated xanthones and biflavanoids from the twigs of Garcinia merguensis |
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Authors: | Kongkiat Trisuwan Vatcharin Rukachaisirikul Souwalak Phongpaichit Nongporn Hutadilok-Towatana |
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Institution: | 1. Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand;2. Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand;3. Department of Microbiology and Natural Products Research Center, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand;4. Department of Biochemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand |
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Abstract: | One new tetraoxygenated xanthone, merguensinone (1), along with one known xanthone, 1,5,6-trihydroxy-2-prenyl-6′,6′-dimethyl-2H-pyrano(2′,3′:3,4)xanthone (2) and five known biflavanoids, (?)-GB-1a (3), (?)-GB-2a (4), (+)-morelloflavone (5), (+)-volkensiflavone (6), and amentoflavone (7) were isolated from the methanol extract from the twigs of Garcinia merguensis. Their antibacterial activity against the standard Staphylococcus aureus ATCC 25923 and methicillin-resistant S. aureus and antioxidation activity with DPPH assay were examined. |
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Keywords: | Xanthone Biflavanoid Antibacterial activity Antioxidation activity |
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