Phenylpropanoid constituents from the seeds of Lithocarpus pachylepis |
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Authors: | Guoxu Ma Haifeng Wu Jingquan Yuan Lizhen Wu Qingxia Zheng Zhaocui Sun Xiaoru Fan Hua Wei Junshan Yang Xudong Xu |
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Institution: | 1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China;2. National Engineering Laboratory of Southwest Endangered Medicinal Resources Development, National Development and Reform Commission, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China;3. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China |
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Abstract: | Five phenylpropanoids including one new compound balanophonin A (1), one new natural compound balanophonin B (2) were isolated from the seeds of Lithocarpus pachylepis for the first time. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, CD, 1D and 2D NMR). All compounds were evaluated for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7. |
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