Phytochemicals from the stem wood of Sorbus lanata (D. Don.) Schauer |
| |
Authors: | Ghias Uddin Abdul Latif Mohammad Arfan Mumtaz Ali Syed Hamid Hussain Thomas J Simpson Russel J Cox Muhammad Iqbal Choudhary |
| |
Institution: | 1. Institute of Chemical Sciences, University of Peshawar, Peshawar, Pakistan;2. School of Chemistry, University of Bristol, Bristol, United Kingdom;3. Department of Chemistry, University of Malakand, Dir, Chakdara, Pakistan;4. International Center for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan |
| |
Abstract: | Three new phenolic compounds, sorlanin (4-(3-(hydroxymethyl)-5-methoxy-7-phenyl-2,3-dihydrobenzob]1,4]dioxin-2-yl)-2-methoxyphenol, 1), sorbanin (2-((3,5-dimethoxy-1,1′-biphenyl]-4-yl)oxy)-1-(4-hydroxy-3-methoxyphenyl)propane-1,3-diol, 2) and sorbalanin (4-(3-(hydroxymethyl)-5,6-dimethoxy-2,3-dihydrobenzob]1,4]dioxino2,3-g]benzofuran-2-yl)-2-methoxyphenol, 3), together with eight known compounds, polystachyol (4), isolariciresinol (5), dihydrodehydrodiconiferyl alcohol (6), tuberculatin (7), ovafolinin E (8), aucuparin (9), 2′-methoxyaucuparin (10), and tetracosyl-3-(3,4-dihydroxyphenyl)acrylate (11), were isolated from Sorbus lanata. The structures of these phytoconstituents were elucidated through extensive spectroscopic techniques, including UV, IR, 1D and 2D NMR, ESI-MS and HRESI-MS experiments. All the compounds except 9 and 10 were isolated for the first time from the genus Sorbus. The isolated compounds were also tested in DPPH radical scavenging reaction where compounds 6, 7, 10 and 11 showed significant activities with IC50 values of 9.2, 11.7, 23.0 and 33.7 μM, respectively. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|