New diprenylated dihyrochalcones from leaves of Artocarpus elasticus |
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| Authors: | Faiqah Ramli Mawardi Rahmani Nur Kartinee Kassim Najihah Mohd Hashim Mohd Aspollah Sukari Abdah Md Akim Rusea Go |
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| Affiliation: | 1. Chemistry Department, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;2. Department of Pharmacy, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia;3. Department of Health Science, Faculty of Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Malaysia;4. Biology Department, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia |
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| Abstract: | Two new diprenylated dihydrochalcones, elastichalcone A 1 and elastichalcone B 2 and three known compounds were isolated from the leaves of Artocarpus elasticus. Their structures were determined by various spectroscopic techniques (UV, IR, MS, 1D-NMR and 2D-NMR). Elastichalcone B 2 and a known compound exhibited good free radical scavenging activity with IC50 values of 11.30 and 11.89 μg/ml, respectively. |
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| Keywords: | Moraceae Dihydrochalcones Free radical scavenger |
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