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Alkaloids from Glycosmis cochinchinensis twigs |
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| Authors: | Tawanun Sripisut Wong Phakhodee Thunwadee Ritthiwigrom Sarot Cheenpracha Uma Prawat Suwanna Deachathai Theeraphan Machan Surat Laphookhieo |
| Institution: | 1. Natural Products Research Laboratory, School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand;2. Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand;3. School of Science, University of Phayao, Phayao 56000, Thailand;4. Laboratory of Natural Products Chemistry, Faculty of Science and Technology, Phuket Rajabhat University, Phuket 83000, Thailand |
| Abstract: | A phytochemical investigation of the twigs of Glycosmis cochinchinensis led to the isolation of two new alkaloids, glycosmisacridone (1) and glycosmisindole (2), together with eight known compounds (3–10). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 9 exhibited moderate antibacterial activity against methicillin-resistant Staphylococcus aureus SK1with an MIC value of 16 μg/mL. |
| Keywords: | Rutaceae Alkaloids Antibacterial activity |
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