Regulation of biosynthesis of monensins on chemically defined medium |
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Authors: | S Pospíšil E Královcová K Stajner J Tax V Krumphanzl Z Vaněk |
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Institution: | (1) Institute of Microbiology, Czechoslovak Academy of Sciences, 142 20 Prague 4 |
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Abstract: | Addition ofL-valine andDL-isoleucine to the cultivation medium ofStreptomyces cinnamonensis was found to affect the ratio of synthesized monensins A and B. In the presence ofL-valine monensin A is synthesized predominantly, whereas in the presence ofDL-isoleucine the production of monensin B increases. |
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