The human kininogen gene (KNG) mapped to chromosome 3q26-qter by analysis of somatic cell hybrids using the polymerase chain reaction |
| |
| Authors: | Fong Dunne Smith David I. Hsieh Wang-Ting |
| |
| Affiliation: | (1) Department of Biological Sciences and Bureau of Biological Research, Rutgers, The State University of New Jersey, C226 Nelson Biological Laboratories, 08855-1059 Piscataway, NJ, USA;(2) Department of Molecular Biology and Genetics, Wayne State University School of Medicine, 48201 Detroit, MI, USA;(3) Clinical Neurogenetics Branch, National Institute of Mental Health, Building 10, Room 3N218, 20892 Bethesda, MD, USA |
| |
| Abstract: | Summary Kinins, peptide products of kininogens, may be involved in hypertensive and diabetic diseases, and inflammatory disorders. The human kininogen gene (KNG) has been mapped to chromosome 3, using a panel of human-hamster somatic cell hybrids by polymerase chain reaction of hybrid DNA with gene-specific primers. KNG was further assigned to 3q26-3qter, using DNA from a second panel of chromosome 3 deletion mapping cell hybrids. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
