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Similarity of the primary sequences of ribosomal RNAs isolated from vegetative and developing cells of Dictyostelium discoideum
Authors:Bambi Batts-Young  Harvey F. Lodish  Allan Jacobson
Affiliation:1. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA;2. Department of Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605 USA
Abstract:Differentiating cell aggregates of Dictyostelium discoideum exhibit a pattern of rRNA metabolism quite different from that observed in the single-celled vegetative amoebas of this organism. We have examined whether the differences are related to a requirement for the production of new types of ribosomal RNA during development. Oligonucleotide maps and supplementary sequence data for 25 S, 17 S, and 5 S rRNAs from vegetative and developing cells have revealed no detectable alterations in primary sequence distinguishing any species of rRNA in developing cells from its vegetative cell counterpart.
Keywords:To whom correspondence and requests for reprints should be addressed.
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