Discussion on “Predictively consistent prior effective sample sizes,” by Beat Neuenschwander,Sebastian Weber,Heinz Schmidli,and Anthony O'Hagan |
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| Authors: | Yeonhee Park Ruitao Lin |
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| Institution: | 1. Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina;2. Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas |
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| Abstract: | We extend the approach of finding effective sample size for a typical phase II clinical trial having efficacy and toxicity as two components of the response vector. The case of binary efficacy and binary toxicity is illustrated under Dirichlet and multivariate T priors. |
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| Keywords: | Dirichlet prior efficacy multivariate T toxicity |
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