Characterization of clinical isolates of group C and G streptococci on the basis of protein G gene |
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Authors: | T Gupalova N Voltchek A Totolyan |
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Institution: | (1) Institute of Experimental Medicine, 197 376 St. Petersburg, Russia |
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Abstract: | Treatment of human group C and G streptococci with cyanogen bromide results in solubilization of surface protein G molecules.
Strain-to-strain variation in the quanity, molar mass and functional activity of protein G extracted from representative group
C and G isolates led to the identification of three structurally and functionally distinct forms of the protein. Using different
molecular biological approaches it was possible to determine the group of streptococci (C or G), or the quantity of IgG and
HSA domains.
Presented at theInternational Conference on Recent Problems in Microbiology and Immunology, Košice (Slovakia), 13–15 October 1999. |
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