Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages |
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Authors: | Kwan Tony Liu Jing Dubow Michael Gros Philippe Pelletier Jerry |
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Affiliation: | McIntyre Medical Sciences Building, Room 810, 3655 Promenade Sir William Osler, McGill University, Montreal, Quebec, Canada H3G 1Y6. |
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Abstract: | A genomic analysis of 18 P. aeruginosa phages, including nine newly sequenced DNA genomes, indicates a tremendous reservoir of proteome diversity, with 55% of open reading frames (ORFs) being novel. Comparative sequence analysis and ORF map organization revealed that most of the phages analyzed displayed little relationship to each other. |
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