Location of genes on chromosome arms in the Anopheles gambiae group of species and their correlation to linkage data for other anopheline mosquitoes |
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Authors: | R. H. HUNT |
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Affiliation: | Department of Tropical Pathology, School of Pathology of the South African Institute for Medical Research, Johannesburg. |
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Abstract: | The use of paracentric inversions as genetic markers in the Anopheles gambiae group of mosquitoes is described. The gene for dieldrin resistance is assigned to chromosome 2 which in turn is correlated to the previous assignment of the gene to linkage group II. The locus of the enzyme phosphoglucomutase 2 (Pgm 2) is similarly assigned to chromosome 2 and evidence is presented for possible linkage between Pgm 2 and dieldrin resistance. There was no linkage or correlation of chromosome 2 and loci of the enzymes superoxide dismutase (Sod) and octanol dehydrogenase (Odh). These genes are therefore assumed to be on chromosome 3 (linkage group III). Evidence that such gene linkage group/chromosome correlations may extend to other species for which chromosome maps and homologies have been worked out is discussed. |
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Keywords: | Anopheles gambiae Anopheles merus gene loci dieldrin resistance polytene chromosomes isoenzymes linkage-group/chromosome correlation malaria vectors |
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