Back to the future: antibody-based strategies for the treatment of infectious diseases |
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Authors: | Oral H Barbaros Ozakin Cüneyt Akdiş Cezmi A |
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Institution: | Department of Microbiology and Infectious Diseases, School of Medicine, Uludag University, Bursa, Turkey. oralb@uludag.edu.tr |
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Abstract: | Before antibiotics, sera from immune animals and humans were used to treat a variety of infectious diseases, often with successful
results. After the discovery of antimicrobial agents, serum therapy for bacterial infections was rapidly forsaken. In the
last two decades, problems with treatment of newly emerged, reemerged, or persistent infectious diseases necessitated researchers
to develop new and/or improved antibody-based therapeutic approaches. This article reviews some information on the use of
antibodies for the treatment of infectious diseases, with special reference to the most seminal discoveries and current advances
as well as available treatment approaches in this field. |
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Keywords: | Antibody therapy infectious diseases immunoglobulin |
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