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The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress
Affiliation:1. Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA;2. Department of Pediatrics, College of Medicine, University of Illinois, Chicago, Illinois, USA;3. Departments of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA;4. Department of Pharmacology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA;5. Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, New Hampshire, USA;1. Bristol Heart Institute, University of Bristol, Level 7, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, UK;2. School of Physiology & Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK
Abstract:
Keywords:Hydrogen peroxide  Ischemia–reperfusion  Langendorff perfusion system  Nrf2  Oxidative stress  Oxygen consumption  Respiration  UCP3  Free radicals
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