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Further Results in Indices for Diagnostic Screening II
Authors:B. M. Bennett
Abstract:This article is in continuation of a previous one on properties of diagnostic indices (Bennett, 1976). Results are presented on biases in sample estimates of the sensitivity (ξ) and specificity (η) of a diagnostic test T for a disease, as well as their asymptotic variances. The problem of combining estimates of ξ, η from various clinical centres and obtaining appropriate confidence limits is also discussed. A numerical example is also given. (Tables 1a, b). The log-linear model for ξ, η is also discussed.
Keywords:Diagnostic tests  sensitivity and specificity  combining estimates  log-linear model
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