FORMATION OF SEROTONIN BY ISOLATED SEROTONIN-CONTAINING NEURONS AND BY ISOLATED NON-AMINE-CONTAINING NEURONS |
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Authors: | G A Cottrell B Powell |
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Institution: | Wellcome Laboratories of Pharmacology and Department of Physiology, University of St. Andrews, Fife, Scotland |
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Abstract: | Isolated giant serotonin-containing neurons of the cerebral ganglia of Helix pomatia were shown to produce serotonin when incubated with 5-hydroxytryptophan (5-HTP) whereas cells of the buccal ganglia, which are non-amine-containing cells did not. The rate of production was comparable to that for Ach in the isolated neurons of Aplysia. The significance of these results is discussed. |
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