The centrosome is a polyfunctional multiprotein cell complex |
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Authors: | I. B. Alieva R. E. Uzbekov |
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Affiliation: | Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russia. irina_alieva@belozersky.msu.ru |
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Abstract: | Contemporary knowledge about centrosome proteins and their ensembles, which can be divided into several functional groups--microtubule-nucleating proteins, microtubule-anchoring proteins, centriole-duplication proteins, cell cycle control proteins, primary cilia growth regulation proteins, and proteins of regulation of cytokinesis--is reviewed. Structural-temporal classification of centrosomal proteins and the scheme of interconnection between the different centrosomal protein complexes are presented. |
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Keywords: | proteins centrosome centriole microtubules cell cycle |
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