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The centrosome is a polyfunctional multiprotein cell complex
Authors:I B Alieva  R E Uzbekov
Institution:Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russia. irina_alieva@belozersky.msu.ru
Abstract:Contemporary knowledge about centrosome proteins and their ensembles, which can be divided into several functional groups--microtubule-nucleating proteins, microtubule-anchoring proteins, centriole-duplication proteins, cell cycle control proteins, primary cilia growth regulation proteins, and proteins of regulation of cytokinesis--is reviewed. Structural-temporal classification of centrosomal proteins and the scheme of interconnection between the different centrosomal protein complexes are presented.
Keywords:proteins  centrosome  centriole  microtubules  cell cycle
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