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Deacetylase inhibitors modulate proliferation and self-renewal properties of leukemic stem and progenitor cells
Authors:Annette Romanski  Kerstin Schwarz  Maren Keller  Sarah Wietbrauk  Anja Vogel  Jessica Roos  Claudia Oancea  Boris Brill  Oliver H Kr?mer  Hubert Serve  Martin Ruthardt  Gesine Bug
Institution:1.Department of Medicine II; Hematology and Oncology; Johann Wolfgang Goethe-University; Frankfurt/Main, Germany;2.Institute for Biomedical Research Georg Speyer-Haus; Frankfurt/Main, Germany;3.Institute of Biochemistry and Biophysics; Center for Molecular Biomedicine; Friedrich-Schiller University; Jena, Germany
Abstract:
Keywords:acute myeloid leukemia  leukemic stem cells  deacetylase inhibitor  BMI1  self-renewal  short-term repopulation  dacinostat  vorinostat
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