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Side effects of atypical antipsychotics: a brief overview
Authors:ALP ÜÇOK  WOLFGANG GAEBEL
Institution:1.WPA Section on Schizophrenia ;2.Department of Psychiatry, Istanbul University Medical Faculty, Millet Street, Capa 34390, Istanbul, Turkey ;3.Department of Psychiatry and Psychotherapy, Heinrich-Heine-University Düsseldorf, Bergische Landstraße 2, D-40629 Düsseldorf, Germany
Abstract:This paper reviews the available evidence concerning the side effects of atypical antipsychotics, including weight gain, type II diabetes mellitus, hyperlipidemia, QTc interval prolongation, myocarditis, sexual side effects, extrapyramidal side effects and cataract. Some recommendations about how to prevent and manage these side effects are also provided. It is concluded that atypical antipsychotics do not represent a homogeneous class, and that differences in side effects should be taken into account by clinicians when choosing an antipsychotic for an individual patient.
Keywords:Schizophrenia  atypical antipsychotics  side effects  treatment guidelines  individual treatment
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