New hydrogel based on polyethylene glycol cross-linked with bovine serum albumin |
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| Authors: | E. M. D'Urso G. Fortier |
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| Affiliation: | (1) Laboratoire d'enzymologie appliquée, Groupe de Recherche en Biothérapeutique Moléculaire, Département de chimie-biochimie, Université du Québec à Montréal, C.P. 8888, succ.Centre-Ville, H3C 3P8 Montréal, Québec, Canada |
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| Abstract: | Summary A new and rapid method for preparing a protaneous-polymeric hydrogel is described. The gel matrix is obtained by covalent cross-linking between preactivated polyethylene glycol of 3350 molecular mass and bovine serum albumin in aqueous solution at basic pH. The polyethylene glycol-albumin hydrogel showed high protein retention and a very good swelling capacity. |
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