Evaluation of oral administration of cortisol and metyrapone: the effects on serum cortisol in rainbow trout (Salmo gairdneri) |
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| Authors: | R O Bennett R C Rhodes |
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| Institution: | 1. Indian Council of Agricultural Research, Central Institute of Fisheries Education, Panch Marg, Yari Road, Versova, Andheri West, Mumbai 400061, India;2. Indian Council of Medical Research Institute, National for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai 400012, India;1. College of Fisheries Science, Gumla, Birsa Agricultural University, Ranchi 834006, India;2. Indian Council of Medical Research-National Institute for Research in Reproductive Health, Mumbai 400012, India;3. Bioinformatics Department, School of Biotechnology and Bioinformatics, D.Y. Patil University, Navi Mumbai 400614, India;4. Indian Council of Agricultural Research-Central Institute of Fisheries Education, Mumbai 400061, India;5. ICAR-CMFRI, Biotechnology Center, Madras, Chennai, India |
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| Abstract: | The effect of manipulating dietary levels of cortisol and metyrapone on peripheral concentrations of serum cortisol was examined in rainbow trout, Salmo gairdneri. Fish were fed 0, 10, 20, 30, 40 or 50 mg/kg body weight/day of metyrapone or cortisol for 7 days. All levels of cortisol tested increased peripheral levels of serum cortisol. Feeding a level of 30-40 mg/kg body weight/day of metyrapone depressed serum cortisol. We describe, herein, a noninvasive technique for suppression or stimulation of serum cortisol in rainbow trout. |
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