Localization of fibronectin in the folliculo-stellate cells of the rat anterior pituitary by the double bridge peroxidase-antiperoxidase method |
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Authors: | Y C Liu S Tanaka K Inoue K Kurosumi |
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Institution: | (1) Department of Morphology, Institute of Endocrinology, Gunma University, 371 Maebashi, Japan |
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Abstract: | Summary The localization of fibronectin was demonstrated in the rat anterior pituitary by the highly sensitive double bridge peroxidase-antiperoxidase (PAP) method. The fibronectin immunopositive cells were characterized by stellatelike morphology. The cells immunostained for fibronectin were observed to be identical to those for S-100 protein in adjacent mirror sections, whereas the S-100 protein has been specifically immunodetected in the folliculo-stellate (FS) cells of the anterior pituitary. The present study indicates that the fibronectin is present in the FS cells, suggesting that FS cells might play a role in the regulation of pituitary function through the interaction of fibronectin with hormone secreting cells |
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