Effect of randomly interesterified triacylglycerol containing medium- and long-chain fatty acids on hepatic fatty acid oxidation after a single administration to rats |
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Authors: | Shinohara Hisami Wu Jian Aoyama Toshiaki |
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Institution: | Central Research Laboratory, The Nisshin OilliO Group, Ltd., Yokosuka, Kanagawa, Japan. h-shinohara@nisshin-oillio.com |
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Abstract: | MLCTs, which are randomly interesterified triacylglycerol containing medium- and long-chain fatty acids in the same glycerol molecule, showed significantly higher acyl-CoA dehydrogenase activity when measured by using butyryl-CoA, octanoyl-CoA, and palmitoyl-CoA as substrates than long-chain triacylglycerol one hour after a single administration to rats. These results suggest that not only medium-chain fatty acid oxidation, but also long-chain fatty acid oxidation were increased in the liver of rats administered with MLCT. |
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